EO 14236 acts as a milestone in the Trump administration’s broader roll-back of regulatory and equity-oriented agendas (e.g., a living wage for federal contractors, collecting data on real-world pandemic outcomes, social justice, etc.). Overall, EO 14236 weakens the U.S. federal government’s ability to support economic growth and health equity by decreasing public health data transparency and research funding (particularly for COVID-19), shifting policy focus from clean energy to minerals, and reducing support for certain marginalized groups. Aside from the specific roll-backs on actions for workers, LGBTQ+ people, and Native Americans, underserved and under-resourced communities across the U.S. will not feel the benefits that COVID-19 data insights, clean energy solutions, and advocacy bring. By rescinding these measures, the Trump administration signals a deliberate shift away from policies designed to enhance the federal infrastructure to address health equity by limiting data transparency, reducing investment in research and innovation, and narrowing the scope of federal priorities that previously supported vulnerable and marginalized populations.